Activin E–ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice

Body fat distribution is a heritable risk factor for cardiovascular and metabolic disease. In humans, rare Inhibin beta E (INHBE, activin E) loss-of-function variants are associated with a lower waist-to-hip ratio and protection from type 2 diabetes. Hepatic fatty acid sensing promotes INHBE express...

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Detalles Bibliográficos
Autores principales: Adam, Rene C., Pryce, Dwaine S., Lee, Joseph S., Zhao, Yuanqi, Mintah, Ivory J., Min, Soo, Halasz, Gabor, Mastaitis, Jason, Atwal, Gurinder S., Aykul, Senem, Idone, Vincent, Economides, Aris N., Lotta, Luca A., Murphy, Andrew J., Yancopoulos, George D., Sleeman, Mark W., Gusarova, Viktoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410708/
https://www.ncbi.nlm.nih.gov/pubmed/37523551
http://dx.doi.org/10.1073/pnas.2309967120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410708/
https://www.ncbi.nlm.nih.gov/pubmed/37523551
http://dx.doi.org/10.1073/pnas.2309967120

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