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Tobacco exposure primes the secretion of CCL21 positively associated with tertiary lymphoid structure and response to immunotherapy

BACKGROUND: It has been reported that smoking history as a predictor of immunotherapy efficacy in patients with advanced lung cancer, however, the underlying mechanisms of this phenomenon remain largely unknown. METHODS: The patients with lung adenocarcinoma’s (LUAD) cohort and the orthotopical tran...

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Detalles Bibliográficos
Autores principales: Yin, Xuewen, Wang, Hui, Li, Rutao, Song, Xuming, Zhang, Te, Liang, Yingkuan, Chen, Yu-Zhong, Yu, Xinnian, Mao, Qixing, Xia, Wenjie, Chen, Bing, Xu, Lin, Dong, Gaochao, Jiang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410842/
https://www.ncbi.nlm.nih.gov/pubmed/37369391
http://dx.doi.org/10.1136/jitc-2023-006939