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Tau deficiency inhibits classically activated macrophage polarization and protects against collagen-induced arthritis in mice

BACKGROUND: Tau protein serves a pro-inflammatory function in neuroinflammation. However, the role of tau in other inflammatory disorders such as rheumatoid arthritis (RA) is less explored. This study is to investigate the role of endogenous tau and the potential mechanisms in the pathogenesis of in...

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Detalles Bibliográficos
Autores principales: Chen, Meng, Fu, Wenyu, Xu, Huiyun, Liu, Chuan-ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410869/
https://www.ncbi.nlm.nih.gov/pubmed/37559125
http://dx.doi.org/10.1186/s13075-023-03133-4