An amino acid transporter subunit as an antibody–drug conjugate target in colorectal cancer

BACKGROUND: Advanced colorectal cancer (CRC) is difficult to treat. For that reason, the development of novel therapeutics is necessary. Here we describe a potentially actionable plasma membrane target, the amino acid transporter protein subunit CD98hc. METHODS: Western blot and immunohistochemical...

Descripción completa

Detalles Bibliográficos
Autores principales: Montero, Juan Carlos, del Carmen, Sofía, Abad, Mar, Sayagués, José M., Barbáchano, Antonio, Fernández-Barral, Asunción, Muñoz, Alberto, Pandiella, Atanasio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410906/
https://www.ncbi.nlm.nih.gov/pubmed/37559159
http://dx.doi.org/10.1186/s13046-023-02784-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410906/
https://www.ncbi.nlm.nih.gov/pubmed/37559159
http://dx.doi.org/10.1186/s13046-023-02784-0

Ejemplares similares