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An amino acid transporter subunit as an antibody–drug conjugate target in colorectal cancer

BACKGROUND: Advanced colorectal cancer (CRC) is difficult to treat. For that reason, the development of novel therapeutics is necessary. Here we describe a potentially actionable plasma membrane target, the amino acid transporter protein subunit CD98hc. METHODS: Western blot and immunohistochemical...

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Detalles Bibliográficos
Autores principales:	Montero, Juan Carlos, del Carmen, Sofía, Abad, Mar, Sayagués, José M., Barbáchano, Antonio, Fernández-Barral, Asunción, Muñoz, Alberto, Pandiella, Atanasio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410906/ https://www.ncbi.nlm.nih.gov/pubmed/37559159 http://dx.doi.org/10.1186/s13046-023-02784-0

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