KITENIN promotes aerobic glycolysis through PKM2 induction by upregulating the c-Myc/hnRNPs axis in colorectal cancer

PURPOSE: The oncoprotein KAI1 C-terminal interacting tetraspanin (KITENIN; vang-like 1) promotes cell metastasis, invasion, and angiogenesis, resulting in shorter survival times in cancer patients. Here, we aimed to determine the effects of KITENIN on the energy metabolism of human colorectal cancer...

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Detalles Bibliográficos
Autores principales: Varlı, Mücahit, Kim, Sung Jin, Noh, Myung-Giun, Kim, Yoon Gyoon, Ha, Hyung-Ho, Kim, Kyung Keun, Kim, Hangun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410973/
https://www.ncbi.nlm.nih.gov/pubmed/37553596
http://dx.doi.org/10.1186/s13578-023-01089-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410973/
https://www.ncbi.nlm.nih.gov/pubmed/37553596
http://dx.doi.org/10.1186/s13578-023-01089-1

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