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Restoring gluconeogenesis by TEF inhibited proliferation and promoted apoptosis and immune surveillance in kidney renal clear cell carcinoma

BACKGROUND: Kidney renal clear cell carcinoma (KIRC) is the major histological subtype of kidney tumor which covers approximately 80% of the cases. Although various therapies have been developed, the clinical outcome remains unsatisfactory. Metabolic dysregulation is a key feature of KIRC, which imp...

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Detalles Bibliográficos
Autores principales: Zhuang, Wenyuan, Shi, Xiaokai, Gao, Shenglin, Qin, Xihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10410999/
https://www.ncbi.nlm.nih.gov/pubmed/37553601
http://dx.doi.org/10.1186/s40170-023-00312-4