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Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth
BACKGROUND: The pancreatic microenvironment has a defensive role against cancer but it can acquire tumor-promoting properties triggered by multiple mechanisms including alterations in the equilibrium between proteases and their inhibitors. The identification of proteolytic events, targets and pathwa...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411016/ https://www.ncbi.nlm.nih.gov/pubmed/37559126 http://dx.doi.org/10.1186/s13046-023-02778-y |