Fibronectin fragments generated by pancreatic trypsin act as endogenous inhibitors of pancreatic tumor growth

BACKGROUND: The pancreatic microenvironment has a defensive role against cancer but it can acquire tumor-promoting properties triggered by multiple mechanisms including alterations in the equilibrium between proteases and their inhibitors. The identification of proteolytic events, targets and pathwa...

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Detalles Bibliográficos
Autores principales: Resovi, Andrea, Persichitti, Perla, Brunelli, Laura, Minoli, Lucia, Borsotti, Patrizia, Garattini, Giulia, Tironi, Matteo, Dugnani, Erica, Redegalli, Miriam, De Simone, Giulia, Pastorelli, Roberta, Bani, Maria Rosa, Piemonti, Lorenzo, Mosher, Deane F., Giavazzi, Raffaella, Taraboletti, Giulia, Belotti, Dorina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411016/
https://www.ncbi.nlm.nih.gov/pubmed/37559126
http://dx.doi.org/10.1186/s13046-023-02778-y

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