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Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway

Cyclophosphamide-induced testosterone deficiency (CPTD) during the treatment of cancers and autoimmune disorders severely influences the quality of life of patients. Currently, several guidelines recommend patients suffering from CPTD receive testosterone replacement therapy (TRT). However, TRT has...

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Detalles Bibliográficos
Autores principales: Liang, Hao-Yu, Peng, Fan, Pan, Min-Jia, Liao, Sen-Lin, Wei, Cun, Wei, Guan-Yang, Xie, Xiao, Xue, Kang-Yi, Chen, Ming-Kun, Yang, Jian-Kun, Guo, Wen-Bin, Liu, Cun-Dong, Zhou, Qi-Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411264/
https://www.ncbi.nlm.nih.gov/pubmed/36537377
http://dx.doi.org/10.4103/aja202286