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Exosomes derived from BMSCs ameliorate cyclophosphamide-induced testosterone deficiency by enhancing the autophagy of Leydig cells via the AMPK-mTOR signaling pathway
Cyclophosphamide-induced testosterone deficiency (CPTD) during the treatment of cancers and autoimmune disorders severely influences the quality of life of patients. Currently, several guidelines recommend patients suffering from CPTD receive testosterone replacement therapy (TRT). However, TRT has...
Autores principales: | Liang, Hao-Yu, Peng, Fan, Pan, Min-Jia, Liao, Sen-Lin, Wei, Cun, Wei, Guan-Yang, Xie, Xiao, Xue, Kang-Yi, Chen, Ming-Kun, Yang, Jian-Kun, Guo, Wen-Bin, Liu, Cun-Dong, Zhou, Qi-Zhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411264/ https://www.ncbi.nlm.nih.gov/pubmed/36537377 http://dx.doi.org/10.4103/aja202286 |
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