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A data-driven machine learning approach for discovering potent LasR inhibitors

The rampant spread of multidrug-resistant Pseudomonas aeruginosa strains severely threatens global health. This severity is compounded against the backdrop of a stagnating antibiotics development pipeline. Moreover, with many promising therapeutics falling short of expectations in clinical trials, t...

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Detalles Bibliográficos
Autores principales: Koh, Christabel Ming Ming, Ping, Lilian Siaw Yung, Xuan, Christopher Ha Heng, Theng, Lau Bee, San, Hwang Siaw, Palombo, Enzo A., Wezen, Xavier Chee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411317/
https://www.ncbi.nlm.nih.gov/pubmed/37552115
http://dx.doi.org/10.1080/21655979.2023.2243416