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Natural variation in codon bias and mRNA folding strength interact synergistically to modify protein expression in Saccharomyces cerevisiae

Codon bias and mRNA folding strength (mF) are hypothesized molecular mechanisms by which polymorphisms in genes modify protein expression. Natural patterns of codon bias and mF across genes as well as effects of altering codon bias and mF suggest that the influence of these 2 mechanisms may vary dep...

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Detalles Bibliográficos
Autores principales: Wienecke, Anastacia N, Barry, Margaret L, Pollard, Daniel A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411576/
https://www.ncbi.nlm.nih.gov/pubmed/37310925
http://dx.doi.org/10.1093/genetics/iyad113