An allelic series of spontaneous Rorb mutant mice exhibit a gait phenotype, changes in retina morphology and behavior, and gene expression signatures associated with the unfolded protein response

The Retinoid-related orphan receptor beta (RORβ) gene encodes a developmental transcription factor and has 2 predominant isoforms created through alternative first exon usage; one specific to the retina and another present more broadly in the central nervous system, particularly regions involved in...

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Detalles Bibliográficos
Autores principales: Murray, George C, Bubier, Jason A, Zinder, Oraya J, Harris, Belinda, Clark, James, Christopher, Mia-Cara, Hanley, Courtany, Tjong, Harianto, Li, Meihong, Ngan, Chew Yee, Reinholdt, Laura, Burgess, Robert W, Tadenev, Abigail L D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Neurogenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411600/
https://www.ncbi.nlm.nih.gov/pubmed/37300435
http://dx.doi.org/10.1093/g3journal/jkad131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411600/
https://www.ncbi.nlm.nih.gov/pubmed/37300435
http://dx.doi.org/10.1093/g3journal/jkad131

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