Regulating tumor glycometabolism and the immune microenvironment by inhibiting lactate dehydrogenase with platinum(iv) complexes

Lactate dehydrogenase (LDH) is a key enzyme involved in the process of glycolysis, assisting cancer cells to take in glucose and generate lactate, as well as to suppress and evade the immune system by altering the tumor microenvironment (TME). Platinum(iv) complexes MDP and DDP were prepared by modi...

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Detalles Bibliográficos
Autores principales: Jin, Suxing, Yin, Enmao, Feng, Chenyao, Sun, Yuewen, Yang, Tao, Yuan, Hao, Guo, Zijian, Wang, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411615/
https://www.ncbi.nlm.nih.gov/pubmed/37564403
http://dx.doi.org/10.1039/d3sc01874a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411615/
https://www.ncbi.nlm.nih.gov/pubmed/37564403
http://dx.doi.org/10.1039/d3sc01874a

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