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Chemical sensors for imaging total cellular aliphatic aldehydes in live cells

Aliphatic aldehydes are reactive electrophilic carbonyls that cross-link with DNA and proteins leading to cellular toxicity and disease pathogenesis. This toxicity is due to the cooperative effect of multiple aldehydes via a common mechanism. Therefore, live-cell imaging of total aliphatic aldehydes...

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Detalles Bibliográficos
Autores principales: Wills, Rachel, Farhi, Jonathan, Czabala, Patrick, Shahin, Sophia, M. Spangle, Jennifer, Raj, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411626/
https://www.ncbi.nlm.nih.gov/pubmed/37564401
http://dx.doi.org/10.1039/d3sc02025h