Impaired Lysosome Reformation in Chloroquine-Treated Retinal Pigment Epithelial Cells

PURPOSE: To model the in vivo effects of chloroquine on the retinal pigment epithelium in experimentally tractable cell culture systems and determine the effects of mild chloroquine treatment on lysosome function and turnover. METHODS: Effects of low-dose chloroquine treatment on lysosomal function...

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Detalles Bibliográficos
Autores principales: Cardoso, M. Helena, Hall, Michael J., Burgoyne, Thomas, Fale, Pedro, Storm, Tina, Escrevente, Cristina, Antas, Pedro, Seabra, Miguel C., Futter, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411645/
https://www.ncbi.nlm.nih.gov/pubmed/37548963
http://dx.doi.org/10.1167/iovs.64.11.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411645/
https://www.ncbi.nlm.nih.gov/pubmed/37548963
http://dx.doi.org/10.1167/iovs.64.11.10

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