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Polypharmacology guided drug repositioning approach for SARS-CoV2

Drug repurposing has emerged as an important strategy and it has a great potential in identifying therapeutic applications for COVID-19. An extensive virtual screening of 4193 FDA approved drugs has been carried out against 24 proteins of SARS-CoV2 (NSP1-10 and NSP12-16, envelope, membrane, nucleopr...

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Detalles Bibliográficos
Autores principales: Jamir, Esther, Sarma, Himakshi, Priyadarsinee, Lipsa, Kiewhuo, Kikrusenuo, Nagamani, Selvaraman, Sastry, G. Narahari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411734/
https://www.ncbi.nlm.nih.gov/pubmed/37556478
http://dx.doi.org/10.1371/journal.pone.0289890