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Structural basis for cross-group recognition of an influenza virus hemagglutinin antibody that targets postfusion stabilized epitope

Plasticity of influenza virus hemagglutinin (HA) conformation increases an opportunity to generate conserved non-native epitopes with unknown functionality. Here, we have performed an in-depth analysis of human monoclonal antibodies against a stem-helix region that is occluded in native prefusion ye...

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Detalles Bibliográficos
Autores principales: Tonouchi, Keisuke, Adachi, Yu, Suzuki, Tateki, Kuroda, Daisuke, Nishiyama, Ayae, Yumoto, Kohei, Takeyama, Haruko, Suzuki, Tadaki, Hashiguchi, Takao, Takahashi, Yoshimasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411744/
https://www.ncbi.nlm.nih.gov/pubmed/37556494
http://dx.doi.org/10.1371/journal.ppat.1011554