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Systematically uncovering the absorbed effective substances of Radix Scutellaria-licorice drug pair in rat plasma against COVID-19 using a combined UHPLC-Q-TOF-MS analysis and target network pharmacology

Radix Scutellaria-Licorice drug pair (RSLDP), a frequently used herbal pair with the effect of clearing heat and detoxifying, is the commonly employed drug pair in TCM prescriptions for the treatment of COVID-19. Until now, the metabolism feature and anti-COVID-19 mechanism of RSLDP have not been fu...

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Detalles Bibliográficos
Autores principales: Wen, Xuqing, Xie, Weiwei, Gao, Juan, Zhang, Dedong, Yang, Mengxin, Zhang, Zhiqing, Du, Yingfeng, Jin, Yiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411761/
https://www.ncbi.nlm.nih.gov/pubmed/37556490
http://dx.doi.org/10.1371/journal.pone.0289121