Combination therapy with budesonide and acetylcysteine alleviates LPS-induced acute lung injury via the miR-381/NLRP3 molecular axis

BACKGROUND: Acute lung injury (ALI) usually has a high morbidity and mortality rate, but the current treatment is relatively scarce. Both budesonide (Bud) and N-acetylcysteine (NAC) exhibit protective effects in ALI, so we further investigated whether they have a synergistic effect on ALI when used...

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Detalles Bibliográficos
Autores principales: Yu, Huimin, Lv, Meifen, Zhang, Shiying, Zou, Kaiwen, Qian, Yan, Lv, Shaokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411794/
https://www.ncbi.nlm.nih.gov/pubmed/37556466
http://dx.doi.org/10.1371/journal.pone.0289818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411794/
https://www.ncbi.nlm.nih.gov/pubmed/37556466
http://dx.doi.org/10.1371/journal.pone.0289818

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