Ethanolaminephosphate cytidylyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major

Glycerophospholipids including phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are vital components of biological membranes. Trypanosomatid parasites of the genus Leishmania can acquire PE and PC via de novo synthesis and the uptake/remodeling of host lipids. In this study, we investigate...

Descripción completa

Detalles Bibliográficos
Autores principales: Basu, Somrita, Pawlowic, Mattie C., Hsu, Fong-Fu, Thomas, Geoff, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411802/
https://www.ncbi.nlm.nih.gov/pubmed/37506172
http://dx.doi.org/10.1371/journal.ppat.1011112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411802/
https://www.ncbi.nlm.nih.gov/pubmed/37506172
http://dx.doi.org/10.1371/journal.ppat.1011112

Ejemplares similares