Cargando…
Ethanolaminephosphate cytidylyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major
Glycerophospholipids including phosphatidylethanolamine (PE) and phosphatidylcholine (PC) are vital components of biological membranes. Trypanosomatid parasites of the genus Leishmania can acquire PE and PC via de novo synthesis and the uptake/remodeling of host lipids. In this study, we investigate...
Autores principales: | Basu, Somrita, Pawlowic, Mattie C., Hsu, Fong-Fu, Thomas, Geoff, Zhang, Kai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411802/ https://www.ncbi.nlm.nih.gov/pubmed/37506172 http://dx.doi.org/10.1371/journal.ppat.1011112 |
Ejemplares similares
-
Ethanolaminephosphate cytidyltransferase is essential for survival, lipid homeostasis and stress tolerance in Leishmania major
por: Basu, Somrita, et al.
Publicado: (2023) -
Phosphatidylcholine synthesis through cholinephosphate cytidylyltransferase is dispensable in Leishmania major
por: Moitra, Samrat, et al.
Publicado: (2019) -
De Novo Synthesis of Phosphatidylcholine Is Essential for the Promastigote But Not Amastigote Stage in Leishmania major
por: Moitra, Samrat, et al.
Publicado: (2021) -
Regulation of Phosphatidylethanolamine Homeostasis—The Critical Role of CTP:Phosphoethanolamine Cytidylyltransferase (Pcyt2)
por: Pavlovic, Zvezdan, et al.
Publicado: (2013) -
Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets
por: Yue, Lambert, et al.
Publicado: (2020)