Small molecule inhibitor of tau self-association in a mouse model of tauopathy: A preventive study in P301L tau JNPL3 mice

Advances in tau biology and the difficulties of amyloid-directed immunotherapeutics have heightened interest in tau as a target for small molecule drug discovery for neurodegenerative diseases. Here, we evaluated OLX-07010, a small molecule inhibitor of tau self-association, for the prevention of ta...

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Detalles Bibliográficos
Autores principales: Davidowitz, Eliot J., Lopez, Patricia, Jimenez, Heidy, Adrien, Leslie, Davies, Peter, Moe, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411817/
https://www.ncbi.nlm.nih.gov/pubmed/37556474
http://dx.doi.org/10.1371/journal.pone.0286523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411817/
https://www.ncbi.nlm.nih.gov/pubmed/37556474
http://dx.doi.org/10.1371/journal.pone.0286523

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