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TNIK is a conserved regulator of glucose and lipid metabolism in obesity

Obesity and type 2 diabetes (T2D) are growing health challenges with unmet treatment needs. Traf2- and NCK-interacting protein kinase (TNIK) is a recently identified obesity- and T2D-associated gene with unknown functions. We show that TNIK governs lipid and glucose homeostasis in Drosophila and mic...

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Detalles Bibliográficos
Autores principales: Pham, T. C. Phung, Dollet, Lucile, Ali, Mona S., Raun, Steffen H., Møller, Lisbeth L. V., Jafari, Abbas, Ditzel, Nicholas, Andersen, Nicoline R., Fritzen, Andreas M., Gerhart-Hines, Zachary, Kiens, Bente, Suomalainen, Anu, Simpson, Stephen J., Salling Olsen, Morten, Kieser, Arnd, Schjerling, Peter, Nieminen, Anni I., Richter, Erik A., Havula, Essi, Sylow, Lykke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411879/
https://www.ncbi.nlm.nih.gov/pubmed/37556547
http://dx.doi.org/10.1126/sciadv.adf7119