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Apolipoprotein-ε4 is associated with higher fecundity in a natural fertility population

In many populations, the apolipoprotein-ε4 (APOE-ε4) allele increases the risk for several chronic diseases of aging, including dementia and cardiovascular disease; despite these harmful effects at later ages, the APOE-ε4 allele remains prevalent. We assess the impact of APOE-ε4 on fertility and its...

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Detalles Bibliográficos
Autores principales: Trumble, Benjamin C., Charifson, Mia, Kraft, Tom, Garcia, Angela R., Cummings, Daniel K., Hooper, Paul, Lea, Amanda J., Eid Rodriguez, Daniel, Koebele, Stephanie V., Buetow, Kenneth, Beheim, Bret, Minocher, Riana, Gutierrez, Maguin, Thomas, Gregory S., Gatz, Margaret, Stieglitz, Jonathan, Finch, Caleb E., Kaplan, Hillard, Gurven, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411886/
https://www.ncbi.nlm.nih.gov/pubmed/37556539
http://dx.doi.org/10.1126/sciadv.ade9797