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The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian

Gene expression inherently gives rise to stochastic variation (“noise”) in the production of gene products. Minimizing noise is crucial for ensuring reliable cellular functions. However, noise cannot be suppressed below a certain intrinsic limit. For constitutively expressed genes, this limit is typ...

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Detalles Bibliográficos
Autores principales: Weidemann, Douglas E., Holehouse, James, Singh, Abhyudai, Grima, Ramon, Hauf, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411910/
https://www.ncbi.nlm.nih.gov/pubmed/37556551
http://dx.doi.org/10.1126/sciadv.adh5138