The minimal intrinsic stochasticity of constitutively expressed eukaryotic genes is sub-Poissonian

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Gene expression inherently gives rise to stochastic variation (“noise”) in the production of gene products. Minimizing noise is crucial for ensuring reliable cellular functions. However, noise cannot be suppressed below a certain intrinsic limit. For constitutively expressed genes, this limit is typ...

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Detalles Bibliográficos
Autores principales: Weidemann, Douglas E., Holehouse, James, Singh, Abhyudai, Grima, Ramon, Hauf, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10411910/
https://www.ncbi.nlm.nih.gov/pubmed/37556551
http://dx.doi.org/10.1126/sciadv.adh5138

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