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Sub-Cluster Identification through Semi-Supervised Optimization of Rare-Cell Silhouettes (SCISSORS) in single-cell RNA-sequencing

MOTIVATION: Single-cell RNA-sequencing (scRNA-seq) has enabled the molecular profiling of thousands to millions of cells simultaneously in biologically heterogenous samples. Currently, the common practice in scRNA-seq is to determine cell type labels through unsupervised clustering and the examinati...

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Detalles Bibliográficos
Autores principales: Leary, Jack R, Xu, Yi, Morrison, Ashley B, Jin, Chong, Shen, Emily C, Kuhlers, Peyton C, Su, Ye, Rashid, Naim U, Yeh, Jen Jen, Peng, Xianlu Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412410/
https://www.ncbi.nlm.nih.gov/pubmed/37498558
http://dx.doi.org/10.1093/bioinformatics/btad449