Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer

Somatic mutations are a hallmark of tumorigenesis and may be useful for non-invasive diagnosis of cancer. We analyzed whole-genome sequencing data from 2,511 individuals in the Pan-Cancer Analysis of Whole Genomes (PCAWG) study as well as 489 individuals from four prospective cohorts and found disti...

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Detalles Bibliográficos
Autores principales: Bruhm, Daniel C., Mathios, Dimitrios, Foda, Zachariah H., Annapragada, Akshaya V., Medina, Jamie E., Adleff, Vilmos, Chiao, Elaine Jiayuee, Ferreira, Leonardo, Cristiano, Stephen, White, James R., Mazzilli, Sarah A., Billatos, Ehab, Spira, Avrum, Zaidi, Ali H., Mueller, Jeffrey, Kim, Amy K., Anagnostou, Valsamo, Phallen, Jillian, Scharpf, Robert B., Velculescu, Victor E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412448/
https://www.ncbi.nlm.nih.gov/pubmed/37500728
http://dx.doi.org/10.1038/s41588-023-01446-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412448/
https://www.ncbi.nlm.nih.gov/pubmed/37500728
http://dx.doi.org/10.1038/s41588-023-01446-3

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