Unbiased chemokine receptor screening reveals similar efficacy of lymph node- and tumor-targeted T cell immunotherapy

Localization is a crucial prerequisite for immune cell function and solid tumors evade immune control by modulating immune cell infiltration into the tumor stroma. Immunosuppressive cells like regulatory T cells are attracted, while cytotoxic CD8(+) T cells are excluded. Engineering CD8(+) T cells w...

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Detalles Bibliográficos
Autores principales: Pachmayr, Ludwig O., Muehlbauer, Anton, Flommersfeld, Sophie, Graml, Franziska, Hoenninger, Julian, von Baumgarten, Louisa, Buchholz, Veit R., Grassmann, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412482/
https://www.ncbi.nlm.nih.gov/pubmed/37301772
http://dx.doi.org/10.1007/s00262-023-03472-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412482/
https://www.ncbi.nlm.nih.gov/pubmed/37301772
http://dx.doi.org/10.1007/s00262-023-03472-w

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