Recurrent atypical teratoid/rhabdoid tumors (AT/RT) reveal discrete features of progression on histology, epigenetics, copy number profiling, and transcriptomics

Atypical teratoid/rhabdoid tumors (AT/RT) are the most common malignant brain tumors manifesting in infancy. They split into four molecular types. The major three (AT/RT-SHH, AT/RT-TYR, and AT/RT-MYC) all carry mutations in SMARCB1, the fourth quantitatively smaller type is characterized by SMARCA4...

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Detalles Bibliográficos
Autores principales: Johann, Pascal D., Altendorf, Lea, Efremova, Emma-Maria, Holsten, Till, Steinbügl, Mona, Nemes, Karolina, Eckhardt, Alicia, Kresbach, Catena, Bockmayr, Michael, Koch, Arend, Haberler, Christine, Antonelli, Manila, DeSisto, John, Schuhmann, Martin U., Hauser, Peter, Siebert, Reiner, Bens, Susanne, Kool, Marcel, Green, Adam L., Hasselblatt, Martin, Frühwald, Michael C., Schüller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412492/
https://www.ncbi.nlm.nih.gov/pubmed/37450044
http://dx.doi.org/10.1007/s00401-023-02608-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412492/
https://www.ncbi.nlm.nih.gov/pubmed/37450044
http://dx.doi.org/10.1007/s00401-023-02608-7

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