Cargando…

Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents

Targeting co-stimulatory receptors promotes the activation and effector functions of anti-tumor lymphocytes. 4-1BB (CD137/TNFSF9), a member of the tumor necrosis factor receptor superfamily (TNFR-SF), is a potent co-stimulatory receptor that plays a prominent role in augmenting effector functions of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Battin, Claire, De Sousa Linhares, Annika, Leitner, Judith, Grossmann, Anna, Lupinek, Daniela, Izadi, Shiva, Castilho, Alexandra, Waidhofer-Söllner, Petra, Grabmeier-Pfistershammer, Katharina, Stritzker, Jochen, Steinberger, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412504/ https://www.ncbi.nlm.nih.gov/pubmed/37310433 http://dx.doi.org/10.1007/s00262-023-03474-8

Ejemplares similares

BTLA inhibition has a dominant role in the cis-complex of BTLA and HVEM
por: Battin, Claire, et al.
Publicado: (2022)

FcγR requirements and costimulatory capacity of Urelumab, Utomilumab, and Varlilumab
por: Leitner, Judith, et al.
Publicado: (2023)

Not All Immune Checkpoints Are Created Equal
por: De Sousa Linhares, Annika, et al.
Publicado: (2018)

Therapeutic PD-L1 antibodies are more effective than PD-1 antibodies in blocking PD-1/PD-L1 signaling
por: De Sousa Linhares, Annika, et al.
Publicado: (2019)

PD-1 Blockade Promotes Emerging Checkpoint Inhibitors in Enhancing T Cell Responses to Allogeneic Dendritic Cells
por: Stecher, Carmen, et al.
Publicado: (2017)

Saturated very long-chain fatty acids regulate macrophage plasticity and invasiveness
por: Zierfuss, Bettina, et al.
Publicado: (2022)

TIM-3 Does Not Act as a Receptor for Galectin-9
por: Leitner, Judith, et al.
Publicado: (2013)

Interrogating ligand-receptor interactions using highly sensitive cellular biosensors
por: Funk, Maximilian A., et al.
Publicado: (2023)

Lack of Induction of RBD-Specific Neutralizing Antibodies despite Repeated Heterologous SARS-CoV-2 Vaccination Leading to Seroconversion and Establishment of T Cell-Specific Memory in a Patient in Remission of Multiple Myeloma
por: Kratzer, Bernhard, et al.
Publicado: (2022)

HIV-1 Adenoviral Vector Vaccines Expressing Multi-Trimeric BAFF and 4-1BBL Enhance T Cell Mediated Anti-Viral Immunity
por: Kanagavelu, Saravana, et al.
Publicado: (2014)

T cell stimulator cells, an efficient and versatile cellular system to assess the role of costimulatory ligands in the activation of human T cells
por: Leitner, Judith, et al.
Publicado: (2010)

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
por: Sundling, Christopher, et al.
Publicado: (2010)

Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates
por: Sundling, Christopher, et al.
Publicado: (2010)

Galectin-3 Decreases 4-1BBL Bioactivity by Crosslinking Soluble and Membrane Expressed 4-1BB
por: Nielsen, Morten Aagaard, et al.
Publicado: (2022)

Anti-Leukemia Activity of MS-275 Histone Deacetylase Inhibitor Implicates 4-1BBL/4-1BB Immunomodulatory Functions
por: Vire, Bérengère, et al.
Publicado: (2009)

Neuropilin-1 Acts as a Receptor for Complement Split Products
por: Battin, Claire, et al.
Publicado: (2019)

Low seroprotection rate for meningococcus serogroup C in the adult HIV-1-infected population in Austria
por: Grabmeier-Pfistershammer, Katharina, et al.
Publicado: (2019)

Activation of 4-1BBL(+) B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma
por: Lee-Chang, Catalina, et al.
Publicado: (2020)

Similarities and differences between native HIV-1 envelope glycoprotein trimers and stabilized soluble trimer mimetics
por: Torrents de la Peña, Alba, et al.
Publicado: (2019)

Enhanced Immunogenicity of Stabilized Trimeric Soluble Influenza Hemagglutinin
por: Weldon, William C., et al.
Publicado: (2010)

BBL Mortality in South Florida: An Update From Ground Zero
por: Garcia, Onelio, et al.
Publicado: (2022)

Late versus non-late presentation of HIV/AIDS: an economic impact analysis
por: Grabmeier-Pfistershammer, K, et al.
Publicado: (2010)

Characterisation of recombinant CD23 in the trimeric complex with IgE and allergen
por: Selb, Regina Maria, et al.
Publicado: (2015)

A review on immunomodulatory effects of BPA analogues
por: Kodila, Anja, et al.
Publicado: (2023)

Multimeric forms of 4-1BBL as stimulators of T cells for adoptive immunotherapy
por: Kornbluth, Richard S, et al.
Publicado: (2014)

Recombinant salmonella-based 4-1BBL vaccine enhances T cell immunity and inhibits the development of colorectal cancer in rats: in vivo effects of vaccine containing 4-1BBL
por: Ye, Jianxin, et al.
Publicado: (2013)

Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer
por: Cao, Liwei, et al.
Publicado: (2018)

Soluble prefusion-closed HIV-envelope trimers with glycan-covered bases
por: Olia, Adam S., et al.
Publicado: (2023)

Current perspectives of SA-4-1BBL in immune modulation during cancer
por: Zhou, Shu-Ni, et al.
Publicado: (2018)

Draft genome sequence of the moderately halophilic bacterium Halobacillus sp. BBL2006
por: Treves, David S., et al.
Publicado: (2018)

Priming with DNA encoding functional trimers and boosting with soluble trimeric protein elicited tier 2 neutralizing antibodies in non-human primates
por: Chakrabarti, BK, et al.
Publicado: (2012)

Bacterial flagellin—a potent immunomodulatory agent
por: Hajam, Irshad A, et al.
Publicado: (2017)

Combined assessment of S‐ and N‐specific IL‐2 and IL‐13 secretion and CD69 neo‐expression for discrimination of post–infection and post‐vaccination cellular SARS‐CoV‐2‐specific immune response
por: Kratzer, Bernhard, et al.
Publicado: (2022)

Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer
por: Derking, Ronald, et al.
Publicado: (2015)

Water Soluble Iron-Based Coordination Trimers as Synergistic Adjuvants for Pancreatic Cancer
por: Cordani, Marco, et al.
Publicado: (2021)

The Change of Immunoactivity of Dendritic Cells Induced by Mouse 4-1BBL Recombinant Adenovirus
por: Youlin, Kuang, et al.
Publicado: (2010)

Combination Immunotherapy with 4-1BBL and CTLA-4 Blockade for the Treatment of Prostate Cancer
por: Youlin, Kuang, et al.
Publicado: (2012)

Effects of the Temperature and Salt Concentration on the Structural Characteristics of the Protein (PDB Code 1BBL)
por: Shao, Dongqing, et al.
Publicado: (2022)

Unraveling Biohydrogen Production and Sugar Utilization Systems in the Electricigen Shewanella marisflavi BBL25
por: Kim, Sang Hyun, et al.
Publicado: (2023)

The Rising Trend of the Reverse Bbl and the Implications for Aesthetic Surgeons: A Google Trends Analysis
por: Safeek, Rachel, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_phloe9gc0uvoaj3e98lgma7n88