Race-specific association of an IRGM risk allele with cytokine expression in human subjects

Immunity-related GTPase family M (IRGM), located on human chromosome 5q33.1, encodes a protein that promotes autophagy and suppresses the innate immune response. The minor allele of rs13361189 (−4299T>C), a single nucleotide polymorphism in the IRGM promoter, has been associated with several dise...

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Detalles Bibliográficos
Autores principales: Ajayi, Teminioluwa, Rai, Prashant, Shi, Min, Gabor, Kristin A., Karmaus, Peer W. F., Meacham, Julie M., Katen, Kevin, Madenspacher, Jennifer H., Schurman, Shepherd H., Fessler, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412543/
https://www.ncbi.nlm.nih.gov/pubmed/37558924
http://dx.doi.org/10.1038/s41598-023-40313-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412543/
https://www.ncbi.nlm.nih.gov/pubmed/37558924
http://dx.doi.org/10.1038/s41598-023-40313-3

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