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Characterizing the role of Phlda3 in the development of acute toxicity and malignant transformation of hematopoietic cells induced by total-body irradiation in mice

The tumor suppressor p53 is a transcriptional factor that plays a crucial role in controlling acute toxicity and long-term malignant transformation of hematopoietic cells induced by genotoxic stress such as ionizing radiation. Among all transcriptional targets of p53, one gene that is robustly induc...

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Detalles Bibliográficos
Autores principales: Hasapis, Stephanie, Caraballo, Isibel, Sears, Timothy J., Brock, Kennedy D., Cart, John B., Moding, Everett J., Lee, Chang-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412554/
https://www.ncbi.nlm.nih.gov/pubmed/37558703
http://dx.doi.org/10.1038/s41598-023-39678-2