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Catalytic site flexibility facilitates the substrate and catalytic promiscuity of Vibrio dual lipase/transferase

Although enzyme catalysis is typified by high specificity, enzymes can catalyze various substrates (substrate promiscuity) and/or different reaction types (catalytic promiscuity) using a single active site. This interesting phenomenon is widely distributed in enzyme catalysis, with both fundamental...

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Detalles Bibliográficos
Autores principales: Wang, Chongyang, Liu, Changshui, Zhu, Xiaochuan, Peng, Quancai, Ma, Qingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412561/
https://www.ncbi.nlm.nih.gov/pubmed/37558668
http://dx.doi.org/10.1038/s41467-023-40455-y