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Cross-species transcriptomics reveals bifurcation point during the arterial-to-hemogenic transition

Hemogenic endothelium (HE) with hematopoietic stem cell (HSC)-forming potential emerge from specialized arterial endothelial cells (AECs) undergoing the endothelial-to-hematopoietic transition (EHT) in the aorta-gonad-mesonephros (AGM) region. Characterization of this AECs subpopulation and whether...

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Detalles Bibliográficos
Autores principales: Mo, Shaokang, Qu, Kengyuan, Huang, Junfeng, Li, Qiwei, Zhang, Wenqing, Yen, Kuangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412572/
https://www.ncbi.nlm.nih.gov/pubmed/37558796
http://dx.doi.org/10.1038/s42003-023-05190-6