The pharmacoepigenomic landscape of cancer cell lines reveals the epigenetic component of drug sensitivity

Aberrant DNA methylation accompanies genetic alterations during oncogenesis and tumour homeostasis and contributes to the transcriptional deregulation of key signalling pathways in cancer. Despite increasing efforts in DNA methylation profiling of cancer patients, there is still a lack of epigenetic...

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Detalles Bibliográficos
Autores principales: Ohnmacht, Alexander Joschua, Rajamani, Anantharamanan, Avar, Göksu, Kutkaite, Ginte, Gonçalves, Emanuel, Saur, Dieter, Menden, Michael Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412573/
https://www.ncbi.nlm.nih.gov/pubmed/37558831
http://dx.doi.org/10.1038/s42003-023-05198-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412573/
https://www.ncbi.nlm.nih.gov/pubmed/37558831
http://dx.doi.org/10.1038/s42003-023-05198-y

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