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The pharmacoepigenomic landscape of cancer cell lines reveals the epigenetic component of drug sensitivity
Aberrant DNA methylation accompanies genetic alterations during oncogenesis and tumour homeostasis and contributes to the transcriptional deregulation of key signalling pathways in cancer. Despite increasing efforts in DNA methylation profiling of cancer patients, there is still a lack of epigenetic...
Autores principales: | Ohnmacht, Alexander Joschua, Rajamani, Anantharamanan, Avar, Göksu, Kutkaite, Ginte, Gonçalves, Emanuel, Saur, Dieter, Menden, Michael Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412573/ https://www.ncbi.nlm.nih.gov/pubmed/37558831 http://dx.doi.org/10.1038/s42003-023-05198-y |
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