A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis

Cholesterol biosynthesis is a highly regulated, oxygen-dependent pathway, vital for cell membrane integrity and growth. In fungi, the dependency on oxygen for sterol production has resulted in a shared transcriptional response, resembling prolyl hydroxylation of Hypoxia Inducible Factors (HIFs) in m...

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Detalles Bibliográficos
Autores principales: Dickson, Anna S., Pauzaite, Tekle, Arnaiz, Esther, Ortmann, Brian M., West, James A., Volkmar, Norbert, Martinelli, Anthony W., Li, Zhaoqi, Wit, Niek, Vitkup, Dennis, Kaser, Arthur, Lehner, Paul J., Nathan, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412576/
https://www.ncbi.nlm.nih.gov/pubmed/37558666
http://dx.doi.org/10.1038/s41467-023-40541-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412576/
https://www.ncbi.nlm.nih.gov/pubmed/37558666
http://dx.doi.org/10.1038/s41467-023-40541-1

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