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Molecular insights into intrinsic transducer-coupling bias in the CXCR4-CXCR7 system

Chemokine receptors constitute an important subfamily of G protein-coupled receptors (GPCRs), and they are critically involved in a broad range of immune response mechanisms. Ligand promiscuity among these receptors makes them an interesting target to explore multiple aspects of biased agonism. Here...

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Detalles Bibliográficos
Autores principales: Sarma, Parishmita, Carino, Carlo Marion C., Seetharama, Deeksha, Pandey, Shubhi, Dwivedi-Agnihotri, Hemlata, Rui, Xue, Cao, Yubo, Kawakami, Kouki, Kumari, Poonam, Chen, Yu-Chih, Luker, Kathryn E., Yadav, Prem N., Luker, Gary D., Laporte, Stéphane A., Chen, Xin, Inoue, Asuka, Shukla, Arun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412580/
https://www.ncbi.nlm.nih.gov/pubmed/37558722
http://dx.doi.org/10.1038/s41467-023-40482-9