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Chemokine expression predicts T cell-inflammation and improved survival with checkpoint inhibition across solid cancers

Immune checkpoint inhibitors (ICI) are highly effective in specific cancers where canonical markers of antitumor immunity are used for patient selection. Improved predictors of T cell-inflammation are needed to identify ICI-responsive tumor subsets in additional cancer types. We investigated associa...

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Detalles Bibliográficos
Autores principales: Romero, Joan Miguel, Titmuss, Emma, Wang, Yifan, Vafiadis, James, Pacis, Alain, Jang, Gun Ho, Zhang, Amy, Golesworthy, Bryn, Lenko, Tatiana, Williamson, Laura M., Grünwald, Barbara, O’Kane, Grainne M., Jones, Steven J. M., Marra, Marco. A., Wilson, Julie M., Gallinger, Steven, Laskin, Janessa, Zogopoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412582/
https://www.ncbi.nlm.nih.gov/pubmed/37558751
http://dx.doi.org/10.1038/s41698-023-00428-2