Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition

Animal mitochondrial gene expression relies on specific interactions between nuclear-encoded aminoacyl-tRNA synthetases and mitochondria-encoded tRNAs. Their evolution involves an antagonistic interplay between strong mutation pressure on mtRNAs and selection pressure to maintain their essential fun...

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Detalles Bibliográficos
Autores principales: Kuhle, Bernhard, Hirschi, Marscha, Doerfel, Lili K., Lander, Gabriel C., Schimmel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412605/
https://www.ncbi.nlm.nih.gov/pubmed/37558671
http://dx.doi.org/10.1038/s41467-023-40354-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412605/
https://www.ncbi.nlm.nih.gov/pubmed/37558671
http://dx.doi.org/10.1038/s41467-023-40354-2

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