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Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition
Animal mitochondrial gene expression relies on specific interactions between nuclear-encoded aminoacyl-tRNA synthetases and mitochondria-encoded tRNAs. Their evolution involves an antagonistic interplay between strong mutation pressure on mtRNAs and selection pressure to maintain their essential fun...
Autores principales: | Kuhle, Bernhard, Hirschi, Marscha, Doerfel, Lili K., Lander, Gabriel C., Schimmel, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412605/ https://www.ncbi.nlm.nih.gov/pubmed/37558671 http://dx.doi.org/10.1038/s41467-023-40354-2 |
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