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Polymerase iota (POLI) confers radioresistance of esophageal squamous cell carcinoma by regulating RAD51 stability and facilitating homologous recombination

Radiotherapy resistance is an important and urgent challenge in the clinical management of esophageal squamous carcinoma (ESCC). However, the factors mediating the ESCC resistance to radiotherapy and its underlying molecular mechanisms are not fully clarified. Our previous studies have demonstrated...

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Detalles Bibliográficos
Autores principales: Li, Xiaoqing, Gao, Dexuan, Shen, Fei, Chen, Hengrui, Zhang, Zhuqiang, He, Chao, Gao, Aidi, Lang, Yue, Zhu, Xiaozhong, Zhou, Jundong, Shang, Zeng-Fu, Ding, Wei-Qun, Zhu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412619/
https://www.ncbi.nlm.nih.gov/pubmed/37558683
http://dx.doi.org/10.1038/s41420-023-01541-8