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Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity

Enhancers function with a basal promoter to control the transcription of target genes. Enhancer regulatory activity is often studied using reporter-based transgene assays. However, unmatched results have been reported when selected enhancers are silenced in situ. In this study, using genomic deletio...

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Detalles Bibliográficos
Autores principales: Sun, Chi, Ruzycki, Philip A., Chen, Shiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412641/
https://www.ncbi.nlm.nih.gov/pubmed/37558693
http://dx.doi.org/10.1038/s41598-023-39979-6