Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains

Since mice do not express a homologue of the human Fc alpha receptor (FcαRI or CD89), a transgenic mouse model was generated in four different backgrounds (C57BL/6, BALB/c, SCID and NXG) expressing the FcαRI under the endogenous human promoter. In this study, we describe previously unknown character...

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Detalles Bibliográficos
Autores principales: Stip, Marjolein C., Jansen, J. H. Marco, Nederend, Maaike, Tsioumpekou, Maria, Evers, Mitchell, Olofsen, Patricia A., Meyer-Wentrup, Friederike, Leusen, Jeanette H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412663/
https://www.ncbi.nlm.nih.gov/pubmed/37338671
http://dx.doi.org/10.1007/s00262-023-03478-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412663/
https://www.ncbi.nlm.nih.gov/pubmed/37338671
http://dx.doi.org/10.1007/s00262-023-03478-4

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