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Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis

BACKGROUND AND AIMS: Donors with fatty livers are considered to address the shortage of livers for transplantation, but those livers are particularly sensitive to ischemia-reperfusion injury (IRI), and an increased incidence of graft failure is observed. Kupffer cells account for 20–35% of liver non...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Wang, Mingfu, An, Ran, Dai, Jun, Liu, Shujun, Chen, Ming, Ding, Haoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412692/
https://www.ncbi.nlm.nih.gov/pubmed/37577223
http://dx.doi.org/10.14218/JCTH.2022.00109