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Activation of NLRP3 Inflammasome via Drp1 Overexpression in Kupffer Cells Aggravates Ischemia-reperfusion Injury in Hepatic Steatosis
BACKGROUND AND AIMS: Donors with fatty livers are considered to address the shortage of livers for transplantation, but those livers are particularly sensitive to ischemia-reperfusion injury (IRI), and an increased incidence of graft failure is observed. Kupffer cells account for 20–35% of liver non...
Autores principales: | Zhang, Lu, Wang, Mingfu, An, Ran, Dai, Jun, Liu, Shujun, Chen, Ming, Ding, Haoran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412692/ https://www.ncbi.nlm.nih.gov/pubmed/37577223 http://dx.doi.org/10.14218/JCTH.2022.00109 |
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