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Cytosolic Ca(2+) gradients and mitochondrial Ca(2+) uptake in resting muscle fibers: A model analysis

Calcium ions (Ca(2+)) enter mitochondria via the mitochondrial Ca(2+) uniporter, driven by electrical and concentration gradients. In this regard, transgenic mouse models, such as calsequestrin knockout (CSQ-KO) mice, with higher mitochondrial Ca(2+) concentrations ([Ca(2+)](mito)), should display h...

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Detalles Bibliográficos
Autores principales: Marcucci, Lorenzo, Michelucci, Antonio, Reggiani, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412765/
https://www.ncbi.nlm.nih.gov/pubmed/37576797
http://dx.doi.org/10.1016/j.bpr.2023.100117